Can blood testing be done in a day of postpartum depression?
Too bad people are diagnosed and treated for postpartum depression. But this blood test could be changed
Elena Medvedeva / Getty Images
Postpartum causes depression (PPD) 10% and 20% Parental Childbirths worldwide, with weak effects, depression, hard humor, removal of family and friends and the inability to link to the child. Although an important diagnosis of the previous depression is a risk factor, many people who have never had a symptom of depression. But the situation can help new research better understand and predicts the situation in which pregnant can search for treatment before creating symptoms.
Investigation, published in January NeuropsychopharmacologyIn addition, 136 people aged 34 to 36 weeks confirmed through a blood draw taken by 136 people Then women diagnosed with PPD had metabolized sex hormone progesterone differently in the third quarter of pregnancy. Progesterona is derived from cholesterol and has many roles, including gamma-aminobutyric acid (GABA), which improves the neurotransmitter that affects the nervous system and improves the feeling of well-being. When progesterona is divided into metabolites, the ratios of these chemicals, known as neurosteroids, can block or help the ability to provide the effects that are soothing.
When the GABA recipients are activated, negative ions emit into the neuron. This loads more negative, which blocks neuronal activities and has a calming effect. But when these recipients do Gabala Shunt, they cannot send negative ions through the neuron and expose the response of stress. PPDs who went to the development of the participants had prone to more progesterona in their blood, as it was not broken down or because Gaba recipients had a greater proportion of Shunt’s metabolites.
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Predicting PPD symptoms is essential for a condition known in the United States in the US diagnoses, treated and opinion about 3% of people with PPD in the US. Lauren M. OsborneAuthor of New Research and Clinical Research Chair in the Department of Bertetrical and Gynecology and Psychiatry at Weill Cornell Medicine. “If you have a blood test to announce postpartum depression, clinicians and patients can immediately give the clinicians and patients immediately postpartum in the host,” he says. The next step will be to repeat the study in a larger and diverse population to see that findings hold. Osborne warned that researchers are a varied steps, creating a profitable blood test that could be used as a regular prenatal care.
“This is important (Postpartum) Depression is often recognized only on a late stage and then the mother and child’s long-term effects are harder,” says Elseline’s hoekzemaPregnancy and Neuroscientist who directs medicine medicine medicine and brain lab and did not participate in the study. If the condition is diagnosed, it can be serious. Suicide today A Main cause of moral mortality It is told in the US 20 percent postpartum deaths.
Osborne says that the blood test also can be used with relatively new treatments that use a similar mechanism to understand the symptoms. A Medications, called ZuranoloneThe US Food and Drug Administration approved in 2023. Allopregnanolone is a synthetic version, the operation of the brain is found to improve the brain. If pregnancly is a lower or higher level of Alopraganolon, it inhibits GABA and affects postpartum depression, the researchers can already have an effective tool for treating those who have already high risk.
Oral medications are not tested for those pregnant, so we don’t know if it is safe for pregnant person or fetus. However, the Portpartum depression symptoms effectively reduces for some people, and achieves full efficiency within two week treatment. This occurs with traditional antidepressants, such as the allegation of serotonin accusation (SSRIS), as they need months to start working.
But there are caves. The medicine could be a problem for new parents who do not have a kindergarten, when drugs are taking, because drugs and fatigue is intense. The new parents who take drugs to respond to someone else’s needs in the course of treating someone else.
Jamie MaguireTufts University Medical School Neuroscience Professor, says the research also points to the clues around those who could go wrong. “In addition to telling the potential biomarker we can use, it also tells us something about the neurobiology under postpartum depression,” says Maguire did not participate in the study. The researcher reaffirms something that has been for years: The cause of the PPD is different from the main depression, which is linked to an imbalance of other brain neurotransmitters, such as serotonin and dopamine.
The discoveries of the new study do not come soon to be meters, lacking treatments and tools, affects Half a million people each year And it does not continue to lead the unfair stigma because so many people suffer silently. “That might really be a big impact for patient care,” says Maguire.
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