The massive Israeli attack took place around 04:00 local time (02:00 GMT) on Saturday, and explosions rocked the city.
In the dark hours of the day, teams of the Ministry of Emergency Situations examined the scene of the incident in Basta, a densely populated area.
Footage showed a plume of smoke rising from a huge crater after one building collapsed.
In recent months, Israeli airstrikes in Beirut have killed several senior members of Hezbollah, including the group’s leader, Hassan Nasrallah.
The Israel Defense Forces (IDF) launched a major offensive against Hezbollah in September, carrying out airstrikes and also sending troops into southern Lebanon.
The hostilities escalated after Iran-backed Hezbollah fired repeated rocket salvos at Israel in solidarity with Hamas, the Palestinian group that carried out a deadly attack on southern Israel on October 7, 2023.
Israel’s stated goal in its war against Hezbollah is to allow the return of some 60,000 residents displaced from communities in northern Israel by the group’s attacks.
In Lebanon, the conflict has killed more than 3,500 people and displaced more than a million, according to Lebanese authorities.
Earlier this week, a US mediator visited Israel and Lebanon in an attempt to secure a ceasefire.
Amos Hochstein noted that some progress had been made, but did not publicly comment on any details.