Microscopic view of paracetamol crystals
Henri Koskin / Shutterstock
The mothers used their mothers paracetamoloIt is also known as Acetaminophen to develop pregnancy Bethd than those who didn’t mother didn’t suggest a small study. While the result is far away, the discovery provides weight, which can affect very used pain relief on fetal brain development.
Previous studies on paracetamol and neurodeopmental conditions have given conflicting discoveries. For example, a 2019 study used more than 4700 children and the use of the Painbiller during pregnancy during pregnancy 20% higher risk among children who develop ADHD. However, a study published last year’s last year’s last year has been shown Not such association They were in front of paracetamol before birth or were not exposed to paracetamol.
A topic is based on using self-reported medications that most of these studies are not remembered to take paracetamole while pregnant. For example, only 7% of the 2019 research reported paracetamol during pregnancy – below 50 percent seen in other studies. “Many people take (paracetamol) without knowing,” he says Brennan Baker Seattle at Washington University. “You could be an active ingredient in cold medicines that you are using, and you don’t know what.”
So Baker and his colleagues used a more detailed metric instead. They searched for medicinal markers in the blood samples collected from 307 women, they were all black and lived in Tennessee, during the second quarter. No one of them took medication to know chronic conditions or pregnancy complications. The researchers then continued with participants when children were between 8 and 10 years old. In the US, About 8 percent of children The ages of 5 and 11 have had TDAH.
On average, mothers who had their mothers in their bloodmarked paracetamol markers who were diagnosed with three times the age of the mother, after adapting factors of pregnancy body mass (BMI), socioeconomic situation and mental health conditions are instant family members. This suggests using paracetamols during pregnancy to increase the risk of developing children’s ADHD.
However, it is possible to raise the risk of the risk of TDAH as someone has brought someone to take paracetamole in the first place. “They were unable to consider things like mother (paracetamol), such as headache or fever or pain or pain or infections, we know that they are risk factors for children’s development,” says Viktor Ahlqvist Swedish Institute of Karolinska.
But the baker believes that the drug is responsible for the same. Analyze a hundred samples from 174 participants plazentrak He showed that those who use Paracetamol changed different metabolic and immune systems. These changes are similar to those seen in the studies that tested the effects of pregnant animals or health conditions.
“In fact, we also see immune-upregulation in animal models, I think, that the case of causality is strengthened,” says Baker. “There is a lot of previous work done during pregnancy that high immune activation is related to the harmful neurodevelopment.”
Still, these findings are inferred. For one thing, the study had a small number of participants, all were black and lived in the same city – limiting the generality of findings. For another, he measured the blood markers of paracetamol at a moment. These markers last about three days, so the exams probably caught more frequent users, and the dose can be dependent on the effect, says Baker.
“(Paracetamol) is the first therapeutic line of pain and fever during pregnancy,” says Baker. “But I think agencies like agencies such as agencies and objective and gynecological associations like US food and drug administration).
Meanwhile, people should talk to doctors whether it should take paracetamole during pregnancy, says Baker.
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